Defined MSC exosome with high yield and purity to improve regenerative activity

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Isolation of Residual Kraft Lignin in High Yield and Purity

In this paper, we report on a novel residual lignin isolation method. Initially we demonstrate that, in order to cellulolytically isolate residual lignin in high yield, the cellulosic structure of the pulp should be exposed as much as possible. Consequently, we developed a two-step method that first uses a mild enzymatic treatment to render most of the carbohydrates water-soluble and remove hem...

متن کامل

a comparison of teachers and supervisors, with respect to teacher efficacy and reflection

supervisors play an undeniable role in training teachers, before starting their professional experience by preparing them, at the initial years of their teaching by checking their work within the proper framework, and later on during their teaching by assessing their progress. but surprisingly, exploring their attributes, professional demands, and qualifications has remained a neglected theme i...

15 صفحه اول

Proteolytic Potential of the MSC Exosome Proteome: Implications for an Exosome-Mediated Delivery of Therapeutic Proteasome

Mesenchymal stem cells (MSCs) are used in many of the current stem cell-based clinical trials and their therapeutic efficacy has increasingly been attributed to secretion of paracrine factors. We have previously demonstrated that a therapeutic constituent of this secretion is exosome, a secreted bilipid membrane vesicle of ~50-100 nm with a complex cargo that is readily internalized by H9C2 car...

متن کامل

Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury.

Human ESC-derived mesenchymal stem cell (MSC)-conditioned medium (CM) was previously shown to mediate cardioprotection during myocardial ischemia/reperfusion injury through large complexes of 50-100 nm. Here we show that these MSCs secreted 50- to 100-nm particles. These particles could be visualized by electron microscopy and were shown to be phospholipid vesicles consisting of cholesterol, sp...

متن کامل

Thematic Analysis of Nursing MSc Theses: a Necessity to Improve the Quality of Nursing Postgraduate Courses

Introduction: Theses as an important part of postgraduate curriculum have a significant role in preparation and empowerment of graduates to participate in research activities. Therefore, proper directions and appropriate use of this opportunity to develop knowledge and special expertise are of great value. The present study aimed to carry out a thematic analysis of nursing MSc theses. Methods:...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Tissue Engineering

سال: 2021

ISSN: 2041-7314,2041-7314

DOI: 10.1177/20417314211008626